fractional flow reserve ppt

Fractional flow reserve FFR-guided treatment has been demonstrated to improve percutaneous coronary intervention PCI results. N Engl J Med.

Fractional Flow Reserve Ffr Dr Md Toufiqur Rahman Fscai Faha Fapsic

Fractional flow reserve FFR utilizes a specialized guide wire to measure blood pressure within a coronary artery.

. Gotberg M et al iFR-SWEDEHEART Investigators. It is not resting flow but maximum achievable flow which determines the functional capacity exercise tolerance of a patient At maximum vasodilation corresponding with maximum hyperemia or with maximum exercise. New England Journal of Medicine 2009.

This determines whether the flow of your blood is healthy or not. A healthy and a normal flow of the blood is considered as 10. Fractional flow reserve FFR and instantaneous wave-free ratio are the present standard diagnostic methods for invasive assessment of the functional significance of epicardial coronary stenosis.

Fractional Flow Reserve Tonino et al. It 1 - Qualifies. In 196 patients undergoing pretranscatheter aortic valve replacement CT fractional flow reserve CT-FFR assessment those with CT-FFR 075.

FFR is defined as a ratio of the maximal myocardial blood flow in the presence of a stenosis to the theoretical normal maximal flow in the same distribution. The original description of FFR required the induction of maximal hyperemia to achieve near linear correlation between coronary pressure and blood flow. As opposed to anatomical approaches physiological measurements particularly pressure-derived FFR assess the function of the coronary circulation and offer the possibility of ad hoc treatment.

FFR and CFR generally have a positive. The mean cost of. Cost effectiveness of instantaneous wave-Free Ratio iFR compared with fractional flow reserve FFR to guide coronary revascularization decision-making.

Instantaneous Wave-free Ratio versus Fractional Flow Reserve to Guide PCI. FFR is defined as the ratio of maximum blood flow in a stenotic artery to maximum blood flow in the same artery if there were no stenosis. Fractional flow reserve FFR is the invasive physiologic gold standard for assessing the clinical significance of coronary arterial stenosis while CFR also known as myocardial flow reserve or MFR is the noninvasive gold standard for assessing the clinical significance of a given coronary stenosis.

ETP course 2014 Sophia-Antipolis FFR. Angio-guided FFR-guided FAME Study. Explanation of postprocedural fractional flow reserve below 085.

A total of 676 of patients in the angiography group and 730 in the FFR group did not have an event and were free from angina at 1 year P007. Fractional flow reserve FFR is emerging as a useful clinical tool for assessing the functional significance of coronary atherosclerosis. 3 SS is an anatomic scoring system based on coronary angiogram.

This clinical outcome in the FFR-guided group was. Fractional flow reserve FFR is a procedure that is based on guide-wire which can appropriately measure the blood pressure and flow via specific part of the coronary artery. Fractional Flow Reserve No Gradient Minimal Moderate Severe.

Fractional flow reserve in clinical practice. In patients with complex three-vessel coronary artery disease CAD PCI guided by measurement of fractional flow reserve FFR with a current generation drug-eluting stent did not meet the criterion for noninferiority compared with CABG in terms of death myocardial infarction MI stroke or revascularization at one year according to findings from FAME 3 trial. Amr Zaki Alexandria University The answer is.

In patients with three-vessel coronary artery disease FFR-guided PCI was not found to be noninferior to CABG with respect to. Fractional flow reserve is the simple ratio of the maximum achievable flow of the diseased coronary artery to the flow of blood in the normal artery. Fractional flow reserve FFR is an invasive measurement developed in 1990s for evaluation of functional significance of stenoses in the epicardial coronary artery.

Fractional flow reserve measurement Induce proper maximal hyperaemia Interpret the tracing appropriately Obtain accurate measurements ETP course 2014 Sophia-Antipolis FFR. Fractional flow reserve measurement based on computed tomography FFRCT is a novel well validated non-invasive method for determining the presence and extent of coronary artery disease CAD combined with a physiological assessment of vessel-specific ischemia in patients with chest pain. 1 The most commonly used pharmacological agent is adenosine as an intravenous infusion.

Fractional flow reserve FFR is a procedure used in coronary catheterization to calculate variations in pressure across coronary artery stenosis. 100 100 60 FFR 060 FFR 085 85 Large Perfusion Area myocardium Small Perfusion Area myocardium MLD cross-sectional area. Thank you for your attention.

The results confirm the long-term safety of FFR-guided PCI in patients with multivessel disease. The index FFR Fractional Flow Reserve is based upon the two following principles. From 2 years to 5 years the risks for both groups developed similarly.

Despite the overall trend towards more physiology-guided revascularization there remains a gap between. Fractional Flow Reserve Distal Pressure Pd Proximal Pressure Pa FFR P d Pa during maximal flow Pd Pa Pd Pa 60 100 FFR 060. A strategy of FFR-guided PCI resulted in a significant decrease of major adverse cardiac events for up to 2 years after the index procedure.

This can easily be measured by the process using a pressure wire. Coronary CT Fractional Flow Reserve before Transcatheter. This process helps to determine the likelihood of stenosis which impedes the supply of.

A standard diagnostic catheter at the time of a coronary angiogram which is also known as cardiac catheterization is used to perform the fractional flow reserve procedure. Should it be routine or individualized according to very specific need in MVD. 1 Fractional Flow Reserve guided Intervention.

Tovar Forero MN Diletti R Lemmert ME Wilschut J de Jaegere PPT Boersma E et al. Fractional Flow Reserve Based on the principle that the distal coronary pressure measured during vasodilation is directly proportional to maximum vasodilated perfusion.

Fractional Flow Reserve